The aim of this research project is to understand how motor and visual plasticity interact in adult humans. We will use psychophysics and non-invasive brain stimulation to study this question. We will investigate how adult ocular dominance plasticity is affected by excitation and inhibition (E/I) balance changes in the motor cortex. Specifically, we will use binocular rivalry and short-term monocular deprivation to study visual plasticity. The motor cortex E/I balance will be manipulated and measured by transcranial magnetic stimulation (TMS), surface electromyography (EMG), and possibly electroencephalogram (EEG).